Dr. Sydney Moïse is involved in teaching, clinical practice, and research. Her research has centered on arrhythmias in dogs. Currently, her research is directed toward the normal and abnormal patterning of cardiac rhythms during long-term Holter analysis.

She also has orchestrated collaborative studies to understand the mechanisms of degeneration of the mitral valve in dogs. She was awarded the AVMA research award for arrhythmia studies in German shepherds and the Bourgelat Award for international contribution to the clinical practice of veterinary medicine.